Mohamed Salah broke Robbie Fowler's record of 128 Premier League goals for LiverpoolLiverpool delivered the complete performance and Mohamed Salah became the club's record Premier League goalscorer as Manchester United were overwhelmed at a joyous Anfield.
United's renaissance under manager Erik ten Hag already has the tangible reward of the Carabao Cup but Liverpool unleashed a brutal reality check on their progress with a severe thrashing.
Liverpool took control of what had been a tight game, with Bruno Fernandes and Marcus Rashford missing presentable chances, when former Old Trafford target Cody Gakpo applied a smooth finish to Andy Robertson's perfect pass two minutes before the break.
The second half was a tale of sheer joy for Liverpool and unrelenting misery for United, starting after 47 minutes when Darwin Nunez's header diverted Harvey Elliott's driven cross past goalkeeper David de Gea.
Salah bamboozled Lisandro Martinez to play in Gakpo for another classy finish three minutes later before the Egyptian resumed his long-time role of United tormentor by getting on the scoresheet himself.
Salah ended a swift counter-attack by lashing a finish high past De Gea and the rout continued as Nunez flashed another header in from Jordan Henderson's cross.
Salah then scrambled in the sixth to become Liverpool's highest Premier League goalscorer with 129, passing Robbie Fowler. He is also Liverpool's highest marksman against Manchester United with 12 - and 10 of those have come in his past five encounters.
And in a fitting finish, Roberto Firmino - who has announced he is leaving Anfield at the end of the season - completed a remarkable game by making it 7-0 from close range.
This is the biggest win in the history of the fixture, passing Liverpool's 7-1 victory in the 1895-96 Second Division.
Liverpool are now an ominous presence in the chase for the Champions League places, standing only three points behind Tottenham with a game in hand.
Liverpool find the fire and fury
Liverpool have resembled a shadow of their real selves this season. The old guarantees, such as intensity and firepower, have been missing far too often.
They all returned here - and how - in the most spectacular manner as Manchester United, who have been undergoing a revival this season, were blown away by a team in full cry.
Once Jurgen Klopp's side took control of a tightly contested game just before half-time, they were ruthless. They scored seven, and missed chances to get more.
Klopp wanted this to be a pivotal week in the race for the top four as his team look to salvage something from a season that has, to this point, been below par.
His players responded. Wolverhampton Wanderers were beaten at Anfield and United, to put it mildly, outclassed.
Liverpool won 5-0 at Old Trafford and 4-0 at Anfield in the Premier League last season while United had a 2-1 win at home early in this campaign to get the Ten Hag era going - and this was another remarkable game to add to that catalogue.
Gakpo was on United's wanted list before he moved to Liverpool in January and his two cool finishes showed why Ten Hag was a fan. Nunez demonstrated his growing threat with a double while Salah always rises to the occasion against United and punished them once more.
There was even the perfect finale of a goal in front of the Kop for Firmino, who announced on Friday he would end a great Liverpool career at the conclusion of this season.
Liverpool manager Klopp resisted a fist pump celebration in front of the Kop - but for him, this day could not have gone any better.
Embarrassment for Man Utd
In seven days, Manchester United have gone from the high of their first trophy since 2017 with the Carabao Cup win against Newcastle United at Wembley to the pain of abject humiliation at Anfield.
Bizarrely, United were right in this game for 43 minutes, with Fernandes and Rashford missing arguably the game's two best chances before Gakpo scored and the sky fell in on Ten Hag's team.
United have had a heavy programme of fixtures but the manner in which they capitulated must be an embarrassment for manager, players and fans. There can be no excuses.
Argentine defender Martinez, normally so reliable and combative, was taken apart, especially when Salah led him a merry dance to set up Gakpo to settle the game with Liverpool's third five minutes after half-time.
To lose against Liverpool is a painful business at any time but to be on the receiving end of what was a record defeat in this fixture will send shock waves through Old Trafford. They must have thought it could not get worse than the 5-0 home thrashing last season - but this was and was inflicted in front of an ecstatic Anfield.
Manchester United must now lick their wounds and return to Europa League action at home to Real Betis on Thursday - and those wounds will hurt after this beating at the home of their arch-rivals.
Player of the match
Mohamed SalahMohamed Salah
Line-ups
Liverpool
Formation 4-3-3
1Alisson
66Alexander-Arnold5Konaté4van Dijk26Robertson
19Elliott3Fabinho14Henderson
11Salah18Gakpo27Núñez
1Alisson66Alexander-Arnold5Konaté4van Dijk26Robertson19ElliottSubstituted forJonesat 85'minutes3FabinhoBooked at 41minsSubstituted forMilnerat 79'minutes14HendersonSubstituted forBajceticat 78'minutes11SalahBooked at 84mins18GakpoSubstituted forFirminoat 79'minutes27NúñezSubstituted forJotaat 78'minutesSubstitutes
7Milner9Firmino17Jones20Jota21Tsimikas28Carvalho32Matip43Bajcetic62KelleherMan Utd
Formation 4-2-3-1
1de Gea
20Dalot19Varane6Li Martínez23Shaw
18Casemiro17Fred
21Antony27Weghorst8Bruno Fernandes
10Rashford
1de Gea20Dalot19Varane6Li MartínezBooked at 61minsSubstituted forMalaciaat 77'minutes23Shaw18CasemiroSubstituted forSabitzerat 77'minutes17FredSubstituted forMcTominayat 58'minutesBooked at 64mins21AntonyBooked at 53mins27WeghorstSubstituted forGarnachoat 58'minutes8Bruno Fernandes10RashfordSubstituted forElangaat 85'minutesSubstitutes
5Maguire12Malacia15Sabitzer22Heaton25Sancho29Wan-Bissaka36Elanga39McTominay49GarnachoLive Text
Match ends, Liverpool 7, Manchester United 0.
Second Half ends, Liverpool 7, Manchester United 0.
Delay over. They are ready to continue.
Delay in match because of an injury Diogo Jota (Liverpool).
Foul by Trent Alexander-Arnold (Liverpool).
Alejandro Garnacho (Manchester United) wins a free kick on the left wing.
Foul by Roberto Firmino (Liverpool).
Marcel Sabitzer (Manchester United) wins a free kick in the attacking half.
Delay over. They are ready to continue.
Delay in match (Liverpool).
Goal! Liverpool 7, Manchester United 0. Roberto Firmino (Liverpool) right footed shot from the right side of the six yard box to the centre of the goal. Assisted by Mohamed Salah with a through ball.
James Milner (Liverpool) wins a free kick on the left wing.
Foul by Antony (Manchester United).
Mohamed Salah (Liverpool) wins a free kick in the defensive half.
Foul by Tyrell Malacia (Manchester United).
Offside, Manchester United. Raphaël Varane tries a through ball, but Alejandro Garnacho is caught offside.
Substitution, Liverpool. Curtis Jones replaces Harvey Elliott.
Substitution, Manchester United. Anthony Elanga replaces Marcus Rashford.
VAR Decision: Goal Liverpool - Liverpool 6-0 Manchester United (Mohamed Salah).
Mohamed Salah (Liverpool) is shown the yellow card for excessive celebration.
Our coverage of your Premier League club is bigger and better than ever before - here's everything you need to know to make sure you never miss a moment
