Britain's Kyle Edmund is ranked 22nd in the world
British number one Kyle Edmund reacted angrily to noise from the crowd during his Miami Open fourth-round defeat by American John Isner.
He was trailing 5-3 in the second set tie-break when the point was stopped after he heard a shout from the crowd.
Umpire Carlos Bernardes ruled Edmund had lost the point as a result, with the Briton saying: "They keep shouting every point, I keep hearing it."
Isner served an ace on the next point to wrap up a 7-6 (7-5) 7-6 (7-3) win.
Defending champion Isner served 17 aces and won 81% of first-serve points as he beat the 19th seed.
Isner raced to an early lead and had treatment on his back before serving for the opening set at 5-3.
However he was broken to love by Edmund, who won two of the final three games to force a tie-break.
The Briton led the tie-break 5-2 but some big serves from Isner and an Edmund double-fault levelled the decider at 5-5, before Isner served out the set.
Eighth seed Isner will face either world number one Novak Djokovic or Spain's Roberto Bautista Agut next.