Youssef En-Nesyri scored his 50th Sevilla goal to put the hosts aheadManchester United were dumped out of the Europa League quarter-finals following a dreadful second-leg performance in defeat by Sevilla.
United were well below their best - creating almost nothing going forward, overrun in midfield and making two terrible mistakes in defence - as they exited Europe with a whimper.
The Spanish side were gifted the lead after eight minutes when Youssef En-Nesyri finished following an awful error from Harry Maguire, and Sevilla doubled their advantage shortly after half time with a looping header from defender Loic Bade.
Sevilla's win - and United's humiliation - was complete nine minutes from time when En-Nesyri again capitalised on a shocking mistake, this time from goalkeeper David de Gea, to complete the win.
Having been 2-0 up and cruising in the first leg at Old Trafford, Erik ten Hag's side contrived to concede five times in the space of 90 minutes - two late own goals in Manchester and three times in Spain - to throw away their chance of European success.
This was the first of a series of potentially season-defining games for United - they take on Brighton at Wembley in the FA Cup semi-finals on Sunday and face a key Premier League match at Tottenham on 27 April - and they completely failed this test.
Sevilla meanwhile will play Juventus in a two-legged semi-final on 11 and 18 May. The Italian side beat Sporting 2-1 on aggregate in their quarter-final.
Maguire blunder begins United nightmare
Having given Sevilla a big helping hand back into the tie with the second own goal in the first leg at Old Trafford, United captain Maguire was found wanting for the opener here.
He was not helped by his goalkeeper, as De Gea played a short pass to him on the edge of the area as three Sevilla players converged in an impressively co-ordinated press.
However Maguire should have done better than play a pass off Erik Lamela, just two yards in front of him. The ball rebounded to En-Nesyri - one of the stars of Morocco's 2022 World Cup exploits - who finished past the hapless De Gea.
It set the mood for the first half, where Sevilla were roared on by the deafening crowd at Ramon Sanchez-Pizjuan Stadium and against a nervous and uncreative United.
Sevilla may sit 13th in La Liga and have spent the majority of a poor season battling relegation, but they looked reinvigorated under Jose Luis Mendillibar, their third permanent manager of the season.
A stunning rabona cross from Nemanja Gudelj after half an hour demonstrated their confidence, while Luis Ocampos appeared to have doubled the lead before the break with a fine finish from the edge of the area only for a lengthy video assistant referee check to determine Marcos Acuna had been narrowly offside in the build-up.
Raucous crowd roars Sevilla into final four
United meanwhile looked bereft of attacking prowess without the suspended Bruno Fernandes or Marcus Rashford, who was on the bench following a groin injury. Anthony Martial started up front against the side where he spent part of last season on loan, but was forced off injured early in the second half.
Rashford, United's top scorer this season, was sent on at half-time to replace the ineffective Jadon Sancho but before he could even have a touch of the ball his side were two goals down.
Ivan Rakitic's corner came off the shoulder of former Nottingham Forest loanee Bade, looped over De Gea and went in off the crossbar.
It summed up a dreadful off-night all around for United - Casemiro was uncharacteristically poor in possession, while in defence the injury enforced absences of Lisandro Martinez and Raphael Varane left gaping chasms of confidence.
But the worst was saved until last. With United chasing the game late on, De Gea rushed out of his goal to try to clear a long ball, only to slice his attempted half-volley and allow En-Nesyri to slot into an empty goal.
Sevilla have now progressed in all seven Uefa Cup and Europa League quarter-finals they have played in, having won all six competitions when they have reached this stage previously.
Player of the match
SusoSuso
Sevilla
Squad number7Player nameSuso
Squad number15Player nameEn-Nesyri
Squad number25Player nameGil
Squad number3Player nameAlex Telles
Squad number10Player nameRakitic
Squad number17Player nameLamela
Squad number55Player nameOcampos
Squad number19Player nameAcuña
Squad number16Player nameNavas
Squad number6Player nameGudelj
Squad number20Player nameFernando
Squad number23Player nameMarcão
Squad number44Player nameBadé
Squad number13Player nameBono
Line-ups
Sevilla
Formation 4-2-3-1
13Bono
16Navas44Badé23do Nascimento Teixeira19Acuña
20Reges6Gudelj
55Ocampos10Rakitic17Lamela
15En-Nesyri
13BonoBooked at 73mins16Navas44Badé23do Nascimento TeixeiraSubstituted forFernández Sáenz de la Torreat 29'minutes19AcuñaSubstituted forAlex Tellesat 85'minutes20Reges6Gudelj55Ocampos10Rakitic17LamelaSubstituted forGilat 80'minutes15En-NesyriSubstitutes
1Dmitrovic3Alex Telles4Rekik7Fernández Sáenz de la Torre12Mir14Nianzou21Torres24Gómez25Gil31FloresMan Utd
Formation 4-2-3-1
1de Gea
29Wan-Bissaka5Maguire2Lindelöf20Dalot
18Casemiro14Eriksen
21Antony15Sabitzer25Sancho
9Martial
1de Gea29Wan-BissakaSubstituted forShawat 45'minutesBooked at 90mins5Maguire2Lindelöf20Dalot18CasemiroBooked at 56mins14EriksenSubstituted forElangaat 87'minutes21AntonyBooked at 59mins15SabitzerSubstituted forFredat 68'minutes25SanchoSubstituted forRashfordat 45'minutes9MartialSubstituted forWeghorstat 54'minutesSubstitutes
10Rashford12Malacia17Fred23Shaw27Weghorst28Pellistri31Butland36Elanga50Vítek55IqbalReferee:Artur Manuel Soares DiasLive Text
Match ends, Sevilla 3, Manchester United 0.
Second Half ends, Sevilla 3, Manchester United 0.
Attempt blocked. Nemanja Gudelj (Sevilla) right footed shot from outside the box is blocked. Assisted by Ivan Rakitic.
Foul by Casemiro (Manchester United).
Ivan Rakitic (Sevilla) wins a free kick in the attacking half.
Luke Shaw (Manchester United) is shown the yellow card for a bad foul.
Foul by Luke Shaw (Manchester United).
Bryan Gil (Sevilla) wins a free kick in the attacking half.
Attempt blocked. Casemiro (Manchester United) right footed shot from outside the box is blocked. Assisted by Fred.
Attempt blocked. Harry Maguire (Manchester United) header from the centre of the box is blocked. Assisted by Antony with a cross.
Corner, Manchester United. Conceded by Jesús Navas.
Corner, Manchester United. Conceded by Nemanja Gudelj.
Attempt blocked. Marcus Rashford (Manchester United) left footed shot from a difficult angle on the left is blocked. Assisted by Luke Shaw with a through ball.
Offside, Sevilla. Lucas Ocampos tries a through ball, but Suso is caught offside.
Attempt saved. Anthony Elanga (Manchester United) right footed shot from outside the box is saved in the bottom left corner. Assisted by Fred.
Marcus Rashford (Manchester United) wins a free kick in the defensive half.
Foul by Alex Telles (Sevilla).
Corner, Sevilla. Conceded by Luke Shaw.
Substitution, Manchester United. Anthony Elanga replaces Christian Eriksen.
Luke Shaw (Manchester United) wins a free kick on the left wing.
